Alexander Solomko Alexander Solomko

українська версія
english version

Birth date: April 26, 1940.

Doctor of science (1994), Head of Department of Biochemical Genetics, Institute of Molecular Biology and Genetics NAS, Ukraine, Kiev. Number of publications: 92.

Education:

1994 - Institute of Molecular Biology & Genetics, Doctor of Science in Molecular Genetics, Thesis: Structural and functional interactions of the Homo- and Heterological Genomes in Eukaryotic Systems

1975 - Institute of Molecular Biology & Genetics, Ph.D. in Biochemistry, Thesis: Studies on Biosynthesis and Structure of Virus-specific RNA of Bombix mori Nuclear Polyhedrosis Virus.

1957-1962 - Kiev State University Master of Science in Biology

Phone: 380 44 526 07 09. Fax: 380 44 526 0759. E-mail: solomko@imbg.org.ua

The fundamental research of the Department encompasses: Investigation of the nucleo-cytoplasmic interactions directing preimplantation mouse development and the problem of the biological clock(s) operating in preimplantation embryo, creation of new methods of directional introduction genetical information in a mammalian genome and study of structure and stability of the transgenomes, investigation of mechanisms of intercellular interactions in agregate chimaeras of mice.

Scientific interests: nucleo-cytoplasmic interactions, preimplantation development,embryo, transgenomes, intercellular interactions, aggregate chimaeras, baculovirus, expression vectors.

Selected Publications :

  1. S.V.Evsikov, L.M.Morozova, A.P.Solomko. The role of the nucleo-cytoplasmic ratio in development regulation of the early mouse embryo/Development, 102:323-328, 1990
  2. S.V.Evsikov, L.M.Morozova, A.P.Solomko. Role of ooplasmic segregation in mammalian development/Roux`s Arch. Develop. Biol. 203:199-204, 1994
  3. M.R.Stolina., A.P.Solomko. The Influence of Low Doses of Chronic Ionizing Radiation on Some Indices of Reproductive Functions of CC57W/Mv Linear Mice from the Chernobyl Population./Tsitologia i Genetica, Vol.30, No.1:53-58.1996.
  4. L.I.Strokovskaya, I.M.Kikhno, N.O.Kalinina, L.I.Chashchina and A.P.Solomko. Expression of Heterologous Proteins in the Baculovirus Vector System: Malacosoma neustria NPV - Antheraea perny Cells/Tsitologia i Genetica, Vol.30, No1:42-48. 1996.
  5. S.V.Evsikov, I.N.Vagina, A.P.Solomko. Mechanisms of Cell Number Regulation in the Peri-Implantantion Mouse Blastocyst./The J.of Exp.Zool., 276:201-208, 1996.
  6. A.P.Solomko, L.I.Strokovskaya. Study of the structure and functional organization of homo- and heterological genomes and their interactions in eukaryotic systems. //Biopolimery i kletka. -14. -N4. -P.343-348, 1998.
  7. Strokovskaya L., Michalik J., Kikhno I., Szolajska E., Solomko A., Ostoja-Zagorski W. Intra- and extracellular expression of human prolactin.//Biochimie.-Supplement Number 6. -FEBS`99. -P. s288.-1999.
  8. Strokovskaya L., Gunkovskaya N., Duzyi D., Solomko A., Szolajska E., Michalik J. Wytwarzanie prolakyny ludszkiej przez rekombinantna bakulowirusa w roznych owadzich liniach komorkowych.//Baculowirusy w biotechnologii. -Poznan. -P.18-21. 1999.
  9. Krysan K.V., Kikhno I.M., Strokovskaya L.I., Solomko A.P. Modification of the DNA structure of plasmid pATV-8 in transgenic mice.3. Analysis of nucleotide sequence of the extrachromosomal transgene and it`s replication in insect cells.//Biopolimery i kletka. -15. -N1. -P.57-62. 1999.
  10. A.V.Evsikov and A.P.Solomko. The Levels and Patterns of Translation in Preimplantation Mouse Embryos with Repressed Cytokinesis./Ontogenez, Vol.30, No2:103-109, 1999.
  11. A.V.Evsikov, A.P.Solomko. Changes in the cavitation start time in chimeric CB6F1-BALB/c embryos.//Tsitol.Genet. -32/-N3. -P.84-87. -1998.
  12. Strokovskaya L., Bartoszewicz Z., Kikhno I., Solomko A, Michailik J. Expression and one-step purification of intracellular human prolactin in insect cells.//Protein Expr.Purif. -22. -N2. -P.242-248. -2001.